Curious about CBD Oil? Maybe there’s a Better Option?
Let’s talk cannabinoids, CBD oil, and doTERRA’s new essential oil, Copaiba.
Cannabinoids – What are they?
Cannabinoids are substances originally identified by researchers investigating the effects of cannabis (hence the name), cannabinoids are sorted into three different categories, based on where they are manufactured:
• Our bodies: endocannabinoids
• Plants: phytocannabinoids
• Chemists: Synthetic cannabinoids
Each cannabinoid interacts in its own specific way with our bodies, via a network of receptors called the endocannabinoid system.
What is the Endocannabinoid System?
Its main function is homeostasis.Homeostasis is the maintenance of a stable environment despite external stresses and changes in the environment. The endocannabinoid system consists of two groups of endocannabinoid receptors:
• Those in your brain and central nervous center are known as CB1 receptors and are predominantly located in the nervous system, connective tissues, gonads, glands, and organs. The CB1 receptors in the brain deal with coordination and movement, pain, emotions and mood, thinking, appetite, and memories, among others. THC attaches to these receptors.
• Those in your immune and endocrine systems are known as CB2 receptors and are primarily found in the immune system, as well as the spleen, liver, heart, kidneys, bones, blood vessels, lymph cells, endocrine glands, and reproductive organs. They have an effect on inflammation and pain.
Let’s talk about marijuana and the cannabis cannabinoids you most likely know:
1. THC, the source of a marijuana, ‘High’
2. CBD, increasingly popular in treating pain, digestive and other inflammatory responses, depression, etc.
THC and CBD interact through both CB1 and CB2 receptors, which means that both affect the brain and central nervous system. The difference is that THC binds well to CB1 receptors, while CBD’s CB1 binding affinity is low. Actually, CBD is not an antagonist at the receptors. Which is why there is not much activity at the CB1 and CB2 receptors. One way it may exert its effect is by inhibiting the enzyme, FAAH. So by inhibiting this enzyme that breaks down endocannabinoids, CBD is inadvertently boosting levels of certain endocannabinoids, like anandamide. CBD acts as a negative allosteric modulator at the CB1 receptor and also targets noncannabinoid receptors like serotonin receptors. This is why it may attenuate the psychoactive effect of THC when given in combination with THC. So, the primary anti-inflammatory agent in cannabis is neither THC or CBD.
Both a cannabinoid and a terpene, beta-caryophyllene is the only terpene known to interact with the endocannabinoid system. It has been studied extensively for its many positive effects as an anti-inflammatory, reducing anxiety, depression and tension, supporting the kidney and liver, protecting against auto-immune issues, and helping ease addictive dependencies. Beta-caryophyllene’s ability to bind effectively with CB2 receptors may actually be responsible for many of the positive effects ascribed to CBD oil.
The primary source for beta-caryophyllene, however, is not cannabis. It is copaiba.
What is ‘Copaiba’?
Derived from Copaifera tree sap, 16th century European visitors found copaiba resin in use by the Mayans. 1625 was its first documentation in a European medical journal. Known for centuries if not millennia, Amazonian and Brazilian traditional healers treat bronchitis, pain, infected tonsils and other illnesses with the resin. It is also widely used in cosmetic products including soaps, creams, lotions, and perfumes.
Benefits of Copaiba Oil
The most effective source for beta-caryophyllene, copaiba oil contains an average of 55% (doTERRA’s copaiba oil has 60%). In contrast, CBD oil only has 35% (and depending on the strength and quality of the CBD compound, what you actually use may deliver as low as 1%). Other plant sources such as clove, helichrysum, basil, black pepper, oregano, rosemary and cinnamon bark contain 6-12% BCPs.
No CB1 interaction
There is no THC and thus no question of psychotropic side effects with copaiba oil. Copaiba does not get you loopy or high. Copaiba will not show up on a drug test. There are no questions of legality.
High ‘bind’ with CB2 receptors
Copaiba’s high concentration of beta-caryophyllene means the highest level of interaction with CB2 receptors and the best efficacy for soothing inflammation throughout the body.
Hemp and marijuana growing standards vary. doTERRA’s rigorous quality requirements and commitment to fair trade and sustainable farming practices mean you don’t need to worry about heavy metals or other contaminants.
CBD oil runs $120+ per 15ml bottle. doTERRA’s copaiba oil, on the other hand, is $35 per 15ml. That comes out to about .60 cents per drop!
Although research is showing benefits of both CBD Oil and Copaiba Oil, the endocannabinoid system is very complex. However, it may be that CBD Oil can also come with unwanted psychological effects. Additionally, what if, antagonizing the system with CBD Oil, may, at times, not be as beneficial as supporting the system long term with an agonist like Copaiba Oil.
1) The following article written by Dr. Cody Beaumont, Director of Analytical Services & Quality Control at dōTERRA, discusses the chemical properties of cannabinoid compounds found in the various cannabis oils. Read the full article here: http://bit.ly/2g6NKMs
2) There is a lot of great research out there on Copaiba and BCP’s, but I need to give a big science shout out to the Gertsch Group at The University of Bern in Switzerland for figuring out how BCP’s affect our health. If you want to dig into the clinical evidence you can read more on their lab website. (http://gertschgroup.com/home/betacaryophyllene_bcp_research)
3) Five reasons Copaiba is better than CBD Oil Posted by John Leavitt, PhD on September 15, 2017 4) Beta-Caryophyllene http://www.doterra.com/US/en/blog/science-research-news-beta-caryophyllene
These statements have not been evaluated by the Food and Drug Administration. None of the products mentioned are intended to diagnose, treat, cure, or prevent any disease.